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Right now, many payers are taking a wait and see approach. Allen noted that some patients are seeing adverse effects when taking these drugs, such as vomiting and nausea, and are likely to regain weight after discontinuing the medications, which also leads to the hesitation

Effects of Lactobacillus casei and Bifidobacterium breve on urinary oxalate excretion in nephrolithiasis patients

And this is what the research actually shows

The 5-oxoproline is then cleaved by a 5-oxoprolinase to yield glutamate, while Cys-Gly is cleaved by specific cys-gly peptidases to yield cysteine and glycine

Put simply, the drug mimics the action of the GLP-1 hormone, but in a much stronger and longer-lasting form

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