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Injecting subcutaneously allows gradual absorption from the injection site over roughly 30-60 minutes

18 Prevention Because of potential interactions from prolonged medication use, physicians should consider screening patients for vitamin B 12 deficiency if they have been taking proton pump inhibitors or H 2 blockers for more than 12 months, or metformin for more than four months

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"Designing Formulation Strategies for Enhanced Stability of Therapeutic Peptides in Aqueous Solutions: A Review." Pharmaceutics , 2023

Mouse studies reported changes in adiposity, glucose handling, liver pathology and muscle-function measurements