which is the best semaglutide vs Tirzepatide: How to Decide for You 1️⃣ How much weight do you want to lose? • Mild to moderate weight loss? Semaglutide (average 12–15%) • Significant weight GLP-1 Weight Loss Medication -

1 These were mostly mild symptoms that resolved quickly

Constipation is a common but manageable Ozempic side effect, affecting about 35% of users

Moreover, in August 2025, Wegovy received accelerated approval to treat metabolic-associated steatohepatitis (MASH) in adults with moderate-to-advanced liver fibrosis (but not cirrhosis)

Ferritin level was lower after placebo compared to semaglutide, but three participants had iron deficiency early in the trial

Heres what experts say about research on the effectiveness of semaglutide (Ozempic, Wegovy)

Clinician-led GLP-1 weight-loss visits that review eligibility , insurance and pharmacy access, side effects , and ongoing follow-up across Nao Medical's NYC and Long Island clinic network