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In the present study, disrupted hepatic glutathione homeostasis was observed in mice chronically exposed to a HFD diet, which is characterized by GSH reduction and GSSG elevation

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Going back to the building blocks of the GSH protein, these non-essential amino acids serve as GSH precursors that enable the body to create Glutathione

90 GPX4 is primarily involved in oxidative lipid metabolism, 91 although the role of GPX4 in lung pathophysiology remains unclear