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vehicle, showing odds ratio, false discovery rate (FDR)adjusted p-value, and enrichment score for each pathway in the liver ( d ), eWAT ( h ) and skeletal muscle ( l )

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They observed that OLE and HOTYR exhibited dose-dependent inhibition on all three activities of this enzyme including 3-processing, strand transfer, and disintegration (112)

Safety, tolerability and pharmacokinetics of PL 14736, a novel agent for treatment of ulcerative colitis, in healthy male volunteers