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For in vivo experiments, total RNA was extracted from the rat retina using the miRNeasy mini kit (QIAGEN, Hilden, Germany) and then reverse-transcribed into cDNA using the SuperScript III First-Strand Synthesis System (Thermo Fisher Scientific, Waltham, MA, USA)

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Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability

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B6 (pyridoxine) Pyridoxine is involved in amino acid metabolism, red blood cell production, and the creation of neurotransmitters

They spread across the oral cavity, mix with saliva, and are easily swallowed accidentally