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Long-Term Effects of Nicotine Use Variations between the immediate and delayed response of the digestive system towards cigarette smoking over short-term or long-term periods are: Short-term effects of nicotine During this period users may observe a sudden alteration in their bowel habits including an increase in frequency accompanied by loose consistency, commonly known as diarrhea

Diabetes Tobacco smoking increases insulin resistance, which will pave the way for type 2 diabetes to take charge

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