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Selenium is included for its ability to bind heavy metals, reducing their toxicity and aiding in their safe removal and Trimethylglycine (TMG) supports liver function and the methylation process, an essential component of detoxification

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Ethacrynic acid concentration screening in the cytoplasm of human hepatocytes The compounds were incubated in liver cytoplasm over a series of time points, and their status as GST substrates was determined by comparing their metabolic trends in the presence and absence of inhibitors

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