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PLOS ONE, [online] 13(6), p.e0198626

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By reducing NO availability and increasing expression of angiotensin-2 and endothelin-1, hyperuricemia shifts the balance between vasodilator and vasoconstrictor stimuli toward vasoconstrictor stimuli increasing the risk for arterial hypertension, endothelial dysfunction, atherosclerosis and vascular adverse events

doi: 10.1016/j.clim.2004.05.004 204 CiorbaMABettonvilleEEMcDonaldKGMetzRPrendergastGCNewberryRDet al

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