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Studies indicate alarming discontinuation rates 53.6% of patients stop GLP-1 therapy within one year, and 72.2% discontinue within two years

Patients who are generally metabolically healthy but require intervention for obesity or overweight

Smokers in the same trial smoked less as well

70,71,72 Moreover, study indicates that combining serum AFP with MTHFD1 enhances the prognostic prediction accuracy in hepatocellular carcinoma (HCC)

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Potential limitations of the study include: Small sample size: With only 52 participants, the study may not have been adequately powered to detect subtle effects