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moreover it is still unclear whether GIP has direct, insulin independent, metabolic effects on adipose tissue

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These changes may also create distributional effects, as some consumers face higher prices than under the status quo, raising equity concerns if lower-income consumers access to affordable protein is strained

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1135,1136 Trimetazidine activates AMPK, enhancing mitochondrial function, insulin sensitivity, and GLUT4 translocation and increasing glucose uptake