Guas de prctica clnica La robusta evidencia sobre el impacto en el riesgo CV ha motivado la inclusin de los AR-GLP1 en el tratamiento de los pacientes con DM2 y ECV aterosclertica y facto res de riesgo CV con un nivel A de recomendacin, as como en aquellos con enfermedad renal 54
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Discussion GLP-1/exendin-4 Suppresses GABA Currents of Rat GCs by Activating GLP-1R Although GLP-1 and GLP-1R agonists have been reported to regulate AMPA receptors and GABA A receptors in central neurons [14, 57,58,59,60], no data concerning the regulation of ligand-gated channels of retinal neurons by GLP-1/GLP-1R agonists were available