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MolProbity: all-atom contacts and structure validation for proteins and nucleic acids

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Abstract Hidradenitis suppurativa is a chronic inflammatory condition characterized by recurrent abscesses, nodules, tunnels, and scarring

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Absence of Human Data: The most critical gap remains the absence of large, well-designed human clinical trials providing conclusive evidence of weight loss

Overall, 50% of patients had evidence of the FDA-approved indication in their medical record (on-label use)