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Metabolic effect by cytochrome P450 It was observed that drugs that undergo extensive metabolism by CYP450 enzymes are generally considered more likely to cause DILI compared to drugs that are not metabolized

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Inhibitory Role of Long non-Coding RNA OIP5-AS1 in Rheumatoid Arthritis Progression Through the microRNA-448-Paraoxonase 1-Toll-Like Receptor 3-Nuclear Factor b Axis

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The application of vitamin E should largely attenuate lipid peroxidation, and therefore was used as a control in our assay to rule out the contribution of small molecule aldehydes generated from ROS 47