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This was an unexpected result insofar that GPX3 is considered a classical Nrf2-induced gene and TNF- has repeatedly been reported to upregulate other Nrf2 target genes in various cell types including leukocytes of the myeloid lineage, vascular endothelial cells, and osteoblasts 50,51,52,53,54

Zhan CD, Sindhu RK, Pang J, Ehdaie A, Vaziri ND