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A further mechanistic consideration is whether the pomegranate extract may have influenced plasma TMAO concentrations partly through its effect on the absorption of L-carnitine in the small intestine, rather than solely through inhibition of microbial TMA production

For validation of the method in plasma and for quality control, human heparinized plasma was pooled and spiked at three different levels with the compounds of interest

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The sample suspension (50 l) was mixed with 200 l Tris-HCl buffer (pH 8.9, 0.8 M) and 10 l 5,5-dithiobis(2-nitrobenzoic acid) (DTNB

At Emerald we believe that the synergistic union of conventional medicine and well-researched integrative health therapies can be the best way to achieve positive patient outcomes