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Common signs include: Fatigue and weakness Numbness or tingling in the hands and feet Difficulty walking or balance problems Mood changes, such as depression or anxiety Cognitive difficulties, including memory loss or confusion If not treated, a B12 deficiency can cause serious problems

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Tingling, numbness, and burning sensations deserve a focused evaluation, especially when symptoms are progressing

The FDA recommends using a non-oral contraceptive method or adding a barrier method for 4 weeks after starting treatment and for 4 weeks after each dose increase