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C., Zuchowski, M
The obvious caveat is that we have only tested GSHee against a 75 mg/kg dose of fentanyl, that while eliciting a substantial degree of ventilatory depression, it does not approach the lethality of higher doses of this opioid
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Further work demonstrated that the p85 subunit had no intrinsic PI3K activity but that it contained a protein-protein interaction domain of the SRC homology domain 3 (SH3) type and two phosphotyrosine-binding sites of the SRC homology domain 2 (SH2) type
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They represent an important component of the inflammatory response in the CNS in response to pathogens and injury [112]
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