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Quitting old-fashioned smokes wont be easy for tobacco companies or their stakeholders

The impact of this disruption is significant, as even a 1 percent annual decline in cigarette volumes represents approximately 125 million packs of combustible cigarettes disappearing from the U.S

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If we are wildly successful, there would be no more patients to use our medicine, says Quigley

While most groups experienced a rise in co-use of cannabis and tobacco, young adults aged 18-25 bucked the trend, with co-use declining after 2014