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Freezing presents a different but equally serious risk

Some patients develop gallbladder problems, including gallstones or even gallbladder inflammation (cholecystitis), during treatment

Dark-colored urine or a significant decrease in urination frequency

Caloric needs vary significantly based on age, sex, activity level, and medical conditions

While mild constipation is manageable with self-care measures, certain symptoms warrant prompt medical evaluation

The confidence in estimates for comparisons between tirzepatide and semaglutide was high to moderate, except for comparisons vs semaglutide 2.0 mg, where the confidence was generally low (ESM Table 8)