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Hvistendahl MK, Naimi RM, Hansen SH, Rehfeld JF, Kissow H, Pedersen J, et al

That's a completely different story

Functional status and well-being in people with myalgic encephalomyelitis/chronic fatigue syndrome compared with people with multiple sclerosis and healthy controls

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When combined, these agents address multiple pathophysiologic defects simultaneously: metformin reduces basal hyperglycemia through hepatic mechanisms, while tirzepatide targets postprandial glucose elevations and promotes weight loss through central appetite regulation

They may also damage your liver and cause inflammation