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The VEGFR2-Akt-eNOS signaling pathway was directly activated (i.e., without the need for other known ligands or shear stress), controlling vasomotor tone (both smooth muscle and endothelium), and the Src-Caveolin-1-eNOS pathway was activated [103,104]

We will examine its molecular mechanisms, the results of clinical and preclinical studies, its potential applications, as well as considerations regarding safety and regulation

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One interfered with pilus biogenesis, and the second impaired its activity (Shaffer et al

Zhao N, Lu XL, Li JT, Zhang JM