Additionally, GIP receptor expression in hypothalamic regions and oligodendrocytes suggests central nervous system actions that may synergize with GLP-1 to reduce appetite and food intake while potentially mitigating GLP-1-associated nausea, thereby improving treatment tolerability [36,41,42]
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Moreover, as a molecular chaperone acting in the early secretory pathway, ERp44 can bind to zinc to control the protein binding and release, thereby managing protein transport and stability
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Here, 1287 patients were randomly assigned in a 1:1:1 ratio to receive rivaroxaban 20 mg ( n = 430), abelacimab 90 mg ( n = 425), or abelacimab 150 mg ( n = 427)