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[9], [10] Age-related changes in cognitive function have a multifactorial origin, with proteasomal dysfunction potentially playing a significant role

Signals for disease modification Evidence for true disease modification remains low-certainty and hypothesis-generating, with recent observational signals serving as a foundation for potential disease modification rather than established therapeutic benefit (100)

Moreover, vitamin D plays a very significant immunoregulatory role in pregnancy

75 (15 Suppl.), 3023 (2015)