The carboxylate group of carnitine forms a salt bridge with the guanidinium group of R471 (TM11), as well as a hydrogen bonding interaction with the hydroxyl of Y447 (TM10), both residues from the C-terminal bundle
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Coenzyme Q10 is another mitochondrial antioxidant that declines with age
In the present study, the beneficial effect of Gln supplementation on inflammation was only mild to moderate, which may be due to the shorter infection period compared to that described by Hagen et al
Arvalo and the rest of the personnel at the Animal Facility (UBAL) at the Institut Pasteur Montevideo for technical assistance with X-ray images and animal care, and A
