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It depends entirely on the concentration

Some early studies from the 1980s and 1990s reported effects on sleep patterns, pain perception, stress hormones, and circadian rhythm, while other investigations failed to find consistent results

This means pigmentation effects accumulate over days, not hours

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(2011) examined the effects of BPC-157 on rats subjected to diclofenac-induced toxicity, which typically causes significant gastrointestinal, liver, and brain lesions