Weight and body composition: Record baseline weight, BMI, and waist circumference
How they work: Rapid digestion and absorption into the bloodstream, enhancing muscle protein synthesis (MPS)
Semaglutide, by stimulating the GLP-1 receptors in the brain, can lower food intake and create a sensation of fullness, resulting in long-term weight loss
The trial enrolled 338 participants across four dose groups plus placebo and ran for 48 weeks
GLP-1 can also block the secretion of glucagon (a hormone capable of raising blood sugar levels), makes you feel full, and reduces the rate of stomach emptying (which can help your body release lower amounts of glucose into your bloodstream)
Researchers are still studying how these Wegovy side effects mental health concerns develop and why responses vary between individuals