This effect makes long-term dietary adherence easier without requiring constant willpower or restrictive eating rules
While steady-state levels are reached within 4 to 5 weeks, clinical effectiveness can vary from person to person
Aim to drink at least 64-80 ounces of plain water daily, more if you exercise or live in a warm climate
People sometimes describe that before taking semaglutide, they were constantly thinking about food, but once that noise was quieted, they found it easier to make the [lifestyle] changes they always wanted, says Gudzune
On top of that, GLP-1 weight-loss medications also slow the rate at which the stomach empties and helps your body respond better to insulin, which keeps blood sugar levels low, further reduces appetite, and can help the body burn fat, Lofton says
This can result from reduced caloric intake (eating significantly less without adjusting activity levels), mild dehydration (reduced food intake often means reduced water intake from food), or blood sugar adjustments as the medication modifies glucose metabolism
