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GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE GLP-1 is a peptide hormone secreted by intestinal enteroendocrine L-cells, specific neurons of the solitary tract in the brainstem and some -cells in the pancreas [28]
Such that, the secretion of inflammatory cytokines, such as tumor necrosis factor- (TNF), would lead to neuroinflammation and migraine episodes by increasing the cellular permeability and interactions (11, 12)
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We previously reported that MSCs with high levels of cellular GSH showed increased stem cell function and therapeutic efficiency in an asthma model [8]
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