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11 While this is a rare adverse effect (ranging from one in 1,000 to one in 3,000 people), this should be discussed with patients before initiating treatment, with advice provided on the symptoms and signs of DKA and when to seek medical attention to get their blood ketones checked (i.e

Fulda S., Gorman A

A typical starting dose is one tablet per day, which can be gradually increased to four tablets per day

C., Ribeiro, P

All these factors have a cascading effect and influence the regular cell cycle, whereby inhibition of apoptosis, reduced accumulation of anti-cancer drugs, and overexpression of oncogenes are common