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One RCT demonstrated improved cardiometabolic risk markers in older adults losing 8% body weight from baseline with energy-restriction and exercise (vs

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A small percentage of Hb is always auto-oxidized under normal physiological conditions resulting in the presence of metHb in blood, but metHb can also be present due to genetic abnormalities, exposure of red cells to certain drugs or toxins, or due to a deficit in antioxidants

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