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In vivo experiments in tail-suspended mouse models confirmed that LASSS treatment significantly reduces HGF nitration and preserves muscle repair signals, offering a promising therapeutic target for sarcopenia, age-related atrophy, and prolonged disuse

Li H, Sun L, Gao P, Hu H

A recent, 2-week, open-label pilot-study in 16 PD patients showed reduced plasma level variability compared to oral IR LD/CD and that DopaFuse treatment over 11 days was associated with matching OFF-time reduction and ON-time gain of 1.7 h [24]

The Benoist 2014 study used the HGF/MET dimerization antagonist Hinge to demonstrate that blocking c-Met activation eliminates Dihexas procognitive effect in scopolamine-impaired rats

Plant Mol Biol 37:8797

doi: 10.1620/tjem.226.251 177 TsaiWCYangYM