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Watch for cloudiness, discoloration, or visible particles, which are signs a vial should no longer be used regardless of how much time has passed since mixing

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In the multicenter SURMOUNT trial, a 72-week treatment with tirzepatide, a dual GLP-1R/GIPR agonist, resulted in a 20.9% reduction in body weight17.7% greater than that observed in the placebo group

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It mimics ghrelin to trigger GH release without spiking cortisol or other unwanted hormones

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