[1] [2] The mechanism of action of Ozempic centres on mimicking the naturally occurring hormone GLP-1, which is released by the intestine in response to food intake
PlexusDx offers the Precision Peptide Genetic Test, which screens for these variants and may help contextualize individual responses to compounded semaglutide or tirzepatide
These include type 2 diabetes and prediabetes (because GLP-1 medications affect blood sugar), thyroid conditions (because of the boxed warning about medullary thyroid carcinoma), a history of pancreatitis (because GLP-1 medications carry a small risk of pancreatitis), gastroparesis or other gastric motility disorders (because GLP-1 medications slow gastric emptying), and any history of eating disorders (because the appetite-suppressing effects of GLP-1 medications require careful management in patients with disordered eating)
Screenings for autism risk begin in early childhood and depression screenings begin at age 12
GLP-1 medications are generally considered safe when prescribed appropriately by a licensed doctor
[DOI] [PMC free article] [PubMed] [Google Scholar] 54.Schafer P.H., Parton A., Gandhi A.K., Capone L., Adams M., Wu L., Bartlett J.B., Loveland M.A., Gilhar A., Cheung Y.F., et al
