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Most of PD cases are sporadic and only a minor subset of overall PD cases is associated to be familial 4,5

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Potential explanations include differences in the type of patients included, adherence to study treatment, sample size, duration of drug exposure, and GLP1 receptor activation with greater HbA1c reduction with longer-acting human GLP1-based analogs than with some short-acting exendin-4 analogs

Cell experiment: Regulatory effect of IGF-1 LR3 on intestinal epithelial cell barrier Intestinal epithelial cell lines, such as Caco-2 cells and IEC-6 cells, are often used to construct in vitro barrier models