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the absorbance of the NAC-treated group was also significantly reduced (Figure 5g), suggesting that NAC reduces membrane permeability

170 MoriT.ShimadaH.ShinotohH.HiranoS.EguchiY.YamadaM.et al (2014)

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On the other hand, major depression is linked to reduced antioxidant levels as well as induced nitrosative and oxidative pathways (Maes et al., 2011)

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These SMADs then heterodimerize with SMAD4 and translocate to the nucleus, where they bind to SMAD-binding elements in genes critical for cartilage matrix production, such as COL2A1 (collagen type II) and ACAN (aggrecan)