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The eGFR profile changes over time with an initial decrease followed by an increase above baseline in eGFR has not been observed with any other pharmacologic interventions, to the best of our knowledge

Back Secher, A, Jelsing, J, Baquero, et al (2014) 'The arcuate nucleus mediates GLP- 1RA liraglutide- dependent weight loss', Journal Clinical Investigation , 124, 447388

In addition to regulating cardiomyocyte function, GLP-1RAs also improve the function of cardiac fibroblasts