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Those with sluggish detoxification pathways

But high intake of Folic Acid on its own can cover up an underlying Vitamin B12 deficiency

Cyanocobalamin, the synthetic form of Vitamin B12, plays an important role in treating and preventing B12 deficiency, especially in individuals with pernicious anemia

The associations were strongest for liver, lung, pancreatic cancers, and myeloid malignancies