In fact, the distal segment of the large intestine can be affected mainly by the circulating components, where both CO and nicotine could modulate the inflammatory profile and leukocyte migration, and the immunomodulatory role would prevail over the impact on the mucosa (Figure 2)
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American Journal of Physiology, 313(2), L193-L206
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A fever indicates that they may have an infection, so its best to make sure your baby doesnt need extra treatment