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These findings suggest that modulating ferroptosis pathways offers targeted benefits for the coronary microvasculature, addressing a specific component of coronary heart disease that often persists despite successful epicardial coronary intervention

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The pivotal Phase 3 NEJM trial documented safety and increased pain-free sun exposure in erythropoietic protoporphyria patients receiving 16mg subcutaneous implants every 60 days (Langendonk et al