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Standard U100 insulin syringes (1 mL capacity) are appropriate for the volumes used in this protocol (0.150.30 mL per injection)
with other medicines for the maintenance treatment of chronic rhinosinusitis with nasal polyposis (CRSwNP) in adults whose disease is not controlled
GLP-1 receptor agonists and GIP/GLP-1 dual agonists carry a deep trial record: STEP studied semaglutide for weight management (NEJM 2021), SURMOUNT studied tirzepatide for weight management (NEJM 2022), and SURMOUNT-OSA studied tirzepatide for obstructive sleep apnea (NEJM 2024)
This is especially true for semaglutide, which is prescribed with a specific titration schedule
Pigo-Zajc D, Mazurek M, Maziarz M, Ochieng Otieno M, Martinez-Useros J, Maecka-Massalska T, Powrzek T
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