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This section explains the molecular mechanism of ROS contribution to the development of disease through signaling and metabolic pathways
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p53 tumour-suppressor caution Because FOXO4-DRI intervenes in the p53 pathway, which is critical for tumour suppression, there is theoretical concern that interfering with p53 dynamics might carry oncogenic risk
After treatment, cells were collected, washed with PBS, and resuspended in binding buffer