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Animal Model:Male Wistar rats (200-225 g, 13-14 weeks old), skin flap model and full-thickness skin wound model [4] Dosage:For the skin flap model, 100 mg/kg (dissolved in drinking water)
Federal Food and Drug Administration (FDA) or the European Medicines Agency (EMA) [26]
Through RNA sequencing analysis, it has been determined that Saikosaponin A primarily affects the glutathione metabolic pathway and suppresses the expression of the cystine transporter protein SLC7A11
For in-vitro laboratory and research use only
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