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Semaglutide, a long-acting GLP-1RA, has been approved for the treatment of T2DM and obesity by the Food and Drug Administration (FDA) (Ala and Moheb 2024)

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Everyone responds differently, but common side effects include: Decreased appetite Nausea Vomiting Indigestion Abdominal pain Constipation Diarrhea To help prevent or reduce side effects: Eat smaller meals (about to of your usual portion size) at regular intervals

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European Review for Medical and Pharmacological Sciences ( Eur Rev Med Pharmacol Sci )