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Pyridoxine hydrochloride boosts several key enzymes needed for testosterone production: 5-alpha-reductase 3-alpha-hydroxysteroid dehydrogenase 17-beta-hydroxysteroid dehydrogenase [11] Men over 60 need enough B6 to keep these enzyme pathways running smoothly

this is more of a supportive measure than an interaction concern

High dose vitamin C (over 5 grams and up to 50 grams) can be incredibly therapeutic, but it is not for people with kidney disease or people with G6PD deficiencies

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It also increases subjective perception of discomfort

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