Although animal models of TAO (induced by sodium laurate) have been generated, the establishment and confirmation of these models are only confirmed by pathological examinations (162, 163)
The central role of CCL2 and CCL7, and thus MoAM, in lung inflammation and pathology is corroborated by a strongly impaired recruitment of monocytes into the lung and protection from pulmonary emphysema upon inhibition of the CCR2/CCL2 axis (72, 78)
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