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As highlighted in a recent review, while GLP-1RAs show potential in treating SLE, further prospective investigations are needed to determine if they pose a risk of triggering autoimmune activity and whether their advantages in SLE outweigh such risks [292]

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The response quality is uneven rather than consistently good or consistently poor

Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist prescribed for weight management in adults, in combination with a reduced calorie diet and exercise