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However, 90-95% of cases of hypertension are essential hypertension

doi: 10.1038/s41467-023-44067-4 [DOI] [PMC free article] [PubMed] [Google Scholar] 213.Zhang B, Cheng Z, Chen J, et al

These preclinical insights have been validated in large-scale clinical trials.The FLOW trial (n = 3,533) showed that once-weekly subcutaneous administration of semaglutide (1.0 mg) significantly reduced the risk of a renal composite endpointincluding 50% decline in eGFR, renal failure, or cardiovascular deathby 24% in patients with T2DM and chronic kidney disease (CKD) (HR = 0.76, 95% CI: 0.660.88

Acta Biomater 4(6):17521761 Semenza GL (2015) AJP-cell theme: cellular responses to hypoxia

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Accessed 7/28/2014