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In a mouse model with Staphylococcus aureus-induced cervical wound infections, the PBOF hydrogel dressing showed antimicrobial activity, utilizing the photothermal properties of ferric ions and polyphenol chelates, together with the hemostatic, antimicrobial, and anti-inflammatory qualities of PCs
[DOI] [PMC free article] [PubMed] [Google Scholar] 93.Samms R.J., Christe M.E., Collins K.A., Pirro V., Droz B.A., Holland A.K., Friedrich J.L., Wojnicki S., Konkol D.L., Cosgrove R., et al
Nie suy do wyliczania dawek, przygotowywania iniekcji ani ustalania sposobu stosowania substancji u ludzi lub zwierzt
Adding KPV to the formulation provides this distinct research category
Comprehensive toxicology studies found no lethal dose even at extremely high levels (20 mg/kg intramuscularly in rats, equivalent to approximately 1,400 mg for a 155 pound human)
While subjective, this observation aligns with the peptides known mechanisms and provides a tangible indicator that something is happening at the tissue level
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