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Importantly, when quantifying synapse numbers in the hippocampus using electron microscopy and Golgi stain methods, it was found that the 3xtg mouse model developed loss of synapses, which was prevented by DA4-JC (Figure 3 for details)

Studies demonstrate that BPC-157 significantly upregulates VEGF expression, promoting the formation of new capillaries to supply healing tissues with oxygen and nutrients [6]